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Another study compared 100 men with MetS to an age- and body mass index-matched control group, results showed that the MetS group had an increased prevalence of ED (26.7% vs 13%), and a sixfold reduction in endothelial function score [14]

10.3389/fimmu.2019.0070531024544 324 Kimura Y, Yanagida T, Onda A, et al

These methods modulate immune pathways by enhancing regulatory T cells (Treg) and regulatory B cells, increasing IgG4 and IgA, and suppressing IgE-mediated activation (Fig

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This information could also guide decisions on whether monotherapy, combination therapy or bariatric surgery is the most appropriate course of action